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Transcranial Magnetic Stimulation for Post-Stroke Dyslexia 1 Case and Clinical Analysis

Received: 30 January 2023     Accepted: 22 February 2023     Published: 28 February 2023
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Abstract

Objective: To investigate the efficacy of repetitive transcranial magnetic stimulation therapy combined with speech training on the speech function of patients with post-stroke aphasia, understanding the mechanisms of cognitive neuropsychological recovery in patients with dyslexia. METHODS: One case of aphasia patients was collected and treated with repetitive transcranial magnetic stimulation and speech therapy, and the patients' Chinese language aphasia examination assessment and hydrogen protons nuclear magnetic resonance spectroscopy results were collected before and after treatment. Based on the combination of neurocognitive psychological model, the relationship between the change of speech function and the dual-channel model before and after patients' repetitive transcranial magnetic stimulation combined with speech therapy was investigated. RESULTS: After 2 months of treatment, the patient's reading function, conversation, comprehension, repetition, and naming function improved when compared with before, and hydrogen protons nuclear magnetic resonance spectroscopy suggested that the patient's bilateral cerebral hemispheres Cr/Ch, and NAA/Cr all increased after treatment compared with before. Conclusion: Transcranial magnetic stimulation therapy combined with speech training can promote the increase of brain metabolites and improve patients' reading function, providing a new therapeutic idea for the treatment of post-stroke dyslexia, Meanwhile, the combination of repetitive transcranial magnetic stimulation technique and hydrogen proton MRI spectroscopy can be used as a non-invasive treatment-examination combination to explore the mechanisms of recovery from dyslexia.

Published in Rehabilitation Science (Volume 8, Issue 1)
DOI 10.11648/j.rs.20230801.11
Page(s) 1-4
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2023. Published by Science Publishing Group

Keywords

Post-Stroke Dyslexia, Transcranial Magnetic Stimulation, Magnetic Resonance Spectroscopy Imaging

References
[1] Obler LK, Albert ML, Goodglass H, Benson DF. aphasia type and aging. brain and Language. 1978; 6 (3): 318-322.
[2] Kaji, Xue-Ping. Cognitive neuropsychological mechanisms of Chinese dyslexia [M.A.], Northwest Normal University; 2007.
[3] Lacey E, Jiang X, Friedman R, et al. Transcranial direct current stimulation for pure alexia: effects on brain and behavior. brain Stimulation: Basic, Translational, and Clinical Research in Neuromodulation. 2015; 8 (2): 305-307.
[4] Coslett HB, Turkeltaub P. Acquired dyslexia. neurobiology of language. 2016: 791-803.
[5] Coltheart M. Writing systems and reading disorders. orthographies and reading: Routledge; 2017: 67-80.
[6] Luo Wei. Types, symptoms and mechanisms of acquired dyslexia. Paper presented at: The 7th Beijing International Rehabilitation Forum 2012; Beijing, China.
[7] Morton J, Patterson K, Coltheart M, Marshall JC. Deep dyslexia 1980.
[8] Tong X, Yip JHY. Cracking the Chinese character: Radical sensitivity in learners of Chinese as a foreign language and its relationship to Chinese word Reading and Writing. 2015; 28 (2): 159-181.
[9] Brown J, Hux K, Fairbanks S. Reading recovery: a case study using a multicomponent treatment for acquired alexia. aphasiology. 2016; 30 (1): 23-44.
[10] Fahmy EM, Elshebawy HM. Effect of High Frequency Transcranial Magnetic Stimulation on Recovery of Chronic Post-Stroke Aphasia. Journal of Stroke 2021/08/01/ 2021; 30 (8): 105855.
[11] Acheson DJ, Hagoort P. Stimulating the brain's language network: syntactic ambiguity resolution after TMS to the inferior frontal gyrus and middle temporal gyrus. journal of cognitive neuroscience. 2013; 25 (10): 1664-1677.
[12] Rubi-Fessen I, Hartmann A, Huber W, et al. Add-on Effects of Repetitive Transcranial Magnetic Stimulation on Subacute Aphasia Therapy: Enhanced Improvement of Functional Communication and Basic Linguistic Skills. A Randomized Controlled Study. Arch Phys Med Rehabil 2015; 96 (11): 1935-44.e2 doi: 10.1016/j.apmr.2015.06.017 [published Online First: Epub Date]|.
[13] Haghighi M, Mazdeh M, Ranjbar N, Seifrabie MA. Further Evidence of the Positive Influence of Repetitive Transcranial Magnetic Stimulation on Speech and Language in Patients with Aphasia after Stroke: Results from a Double-Blind Intervention with Sham Condition. Neuropsychobiology 2017; 75 (4): 185-92 doi: 10.1159/000486144 [published Online First: Epub Date]|.
[14] Ren C, Zhang G, Xu X, et al. The Effect of rTMS over the Different Targets on Language Recovery in Stroke Patients with Global Aphasia: A Randomized Sham-Controlled Study. Biomed Res Int 2019; 4589056 doi: 10.1155/2019/4589056 [published Online First: Epub Date]|.
[15] Goodglass H, Budin C. Category and modality specific dissociations in word comprehension and concurrent phonological dyslexia. Neuropsychologia 1988; 26 (1): 67-78.
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  • APA Style

    Yong Qin Xie, Hong Wang. (2023). Transcranial Magnetic Stimulation for Post-Stroke Dyslexia 1 Case and Clinical Analysis. Rehabilitation Science, 8(1), 1-4. https://doi.org/10.11648/j.rs.20230801.11

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    ACS Style

    Yong Qin Xie; Hong Wang. Transcranial Magnetic Stimulation for Post-Stroke Dyslexia 1 Case and Clinical Analysis. Rehabil. Sci. 2023, 8(1), 1-4. doi: 10.11648/j.rs.20230801.11

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    AMA Style

    Yong Qin Xie, Hong Wang. Transcranial Magnetic Stimulation for Post-Stroke Dyslexia 1 Case and Clinical Analysis. Rehabil Sci. 2023;8(1):1-4. doi: 10.11648/j.rs.20230801.11

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  • @article{10.11648/j.rs.20230801.11,
      author = {Yong Qin Xie and Hong Wang},
      title = {Transcranial Magnetic Stimulation for Post-Stroke Dyslexia 1 Case and Clinical Analysis},
      journal = {Rehabilitation Science},
      volume = {8},
      number = {1},
      pages = {1-4},
      doi = {10.11648/j.rs.20230801.11},
      url = {https://doi.org/10.11648/j.rs.20230801.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.rs.20230801.11},
      abstract = {Objective: To investigate the efficacy of repetitive transcranial magnetic stimulation therapy combined with speech training on the speech function of patients with post-stroke aphasia, understanding the mechanisms of cognitive neuropsychological recovery in patients with dyslexia. METHODS: One case of aphasia patients was collected and treated with repetitive transcranial magnetic stimulation and speech therapy, and the patients' Chinese language aphasia examination assessment and hydrogen protons nuclear magnetic resonance spectroscopy results were collected before and after treatment. Based on the combination of neurocognitive psychological model, the relationship between the change of speech function and the dual-channel model before and after patients' repetitive transcranial magnetic stimulation combined with speech therapy was investigated. RESULTS: After 2 months of treatment, the patient's reading function, conversation, comprehension, repetition, and naming function improved when compared with before, and hydrogen protons nuclear magnetic resonance spectroscopy suggested that the patient's bilateral cerebral hemispheres Cr/Ch, and NAA/Cr all increased after treatment compared with before. Conclusion: Transcranial magnetic stimulation therapy combined with speech training can promote the increase of brain metabolites and improve patients' reading function, providing a new therapeutic idea for the treatment of post-stroke dyslexia, Meanwhile, the combination of repetitive transcranial magnetic stimulation technique and hydrogen proton MRI spectroscopy can be used as a non-invasive treatment-examination combination to explore the mechanisms of recovery from dyslexia.},
     year = {2023}
    }
    

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    T1  - Transcranial Magnetic Stimulation for Post-Stroke Dyslexia 1 Case and Clinical Analysis
    AU  - Yong Qin Xie
    AU  - Hong Wang
    Y1  - 2023/02/28
    PY  - 2023
    N1  - https://doi.org/10.11648/j.rs.20230801.11
    DO  - 10.11648/j.rs.20230801.11
    T2  - Rehabilitation Science
    JF  - Rehabilitation Science
    JO  - Rehabilitation Science
    SP  - 1
    EP  - 4
    PB  - Science Publishing Group
    SN  - 2637-594X
    UR  - https://doi.org/10.11648/j.rs.20230801.11
    AB  - Objective: To investigate the efficacy of repetitive transcranial magnetic stimulation therapy combined with speech training on the speech function of patients with post-stroke aphasia, understanding the mechanisms of cognitive neuropsychological recovery in patients with dyslexia. METHODS: One case of aphasia patients was collected and treated with repetitive transcranial magnetic stimulation and speech therapy, and the patients' Chinese language aphasia examination assessment and hydrogen protons nuclear magnetic resonance spectroscopy results were collected before and after treatment. Based on the combination of neurocognitive psychological model, the relationship between the change of speech function and the dual-channel model before and after patients' repetitive transcranial magnetic stimulation combined with speech therapy was investigated. RESULTS: After 2 months of treatment, the patient's reading function, conversation, comprehension, repetition, and naming function improved when compared with before, and hydrogen protons nuclear magnetic resonance spectroscopy suggested that the patient's bilateral cerebral hemispheres Cr/Ch, and NAA/Cr all increased after treatment compared with before. Conclusion: Transcranial magnetic stimulation therapy combined with speech training can promote the increase of brain metabolites and improve patients' reading function, providing a new therapeutic idea for the treatment of post-stroke dyslexia, Meanwhile, the combination of repetitive transcranial magnetic stimulation technique and hydrogen proton MRI spectroscopy can be used as a non-invasive treatment-examination combination to explore the mechanisms of recovery from dyslexia.
    VL  - 8
    IS  - 1
    ER  - 

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Author Information
  • Department of Rehabilitation, Jinan University, Guangzhou, China

  • Department of Rehabilitation, The First Affiliated Hospital of Jinan University, Jinan University, Guangzhou, China

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